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Antidiabetic drugs

Antidiabetic drugs are medicines that help control blood sugar levels in people with diabetes mellitus (sugar diabetes).

Purpose

Diabetes may be divided into type I and type II, formerly termed juvenile onset or insulin-dependent, and maturity onset or non insulin-dependent. Type I is caused by a deficiency of insulin production, while type II is characterized by insulin resistance.

Treatment of type I diabetes is limited to insulin replacement, while type II diabetes is treatable by a number of therapeutic approaches. Many cases of insulin resistance are asymptomatic due to normal increases in insulin secretion, and others may be controlled by diet and exercise. Drug therapy may be directed toward increasing insulin secretion, increasing insulin sensitivity, or increasing insulin penetration of the cells.

Description:

Antidiabetic drugs may be subdivided into six groups: insulin, sufonylureas, alpha-glucosidase inhibitors, biguanides, meglitinides, and thiazolidinediones.